The Study of Captopril Floating Matrix Tablets Using Different Polymers as Release Retarding Agent

Abstract

The study explores various approaches to enhance the gastric residence time of Captopril dosage forms, which can be achieved through different systems like effervescent, non-effervescent single/multiple unit dosage forms, high-density systems, swellable systems, and more. The floating drug delivery system tested here involves Captopril matrix tablets made with Hydroxypropyl Methylcellulose (HPMC) in varying ratios.